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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
36.06
Human Site:
S543
Identified Species:
56.67
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S543
L
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Chimpanzee
Pan troglodytes
XP_510301
627
67581
D495
I
H
R
D
I
K
S
D
S
I
L
L
T
L
D
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S543
L
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Dog
Lupus familis
XP_544614
968
105825
S830
L
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S544
L
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Rat
Rattus norvegicus
Q62829
544
60692
I412
D
F
G
F
C
A
Q
I
T
P
E
Q
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
D507
F
C
A
Q
I
S
K
D
V
P
K
R
K
S
L
Chicken
Gallus gallus
XP_426393
667
74767
S529
L
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Frog
Xenopus laevis
NP_001082100
650
73749
S516
H
D
G
R
V
K
L
S
D
F
G
F
C
A
Q
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S555
L
D
G
R
I
K
L
S
D
F
G
F
C
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
G507
R
V
K
L
S
D
F
G
F
C
A
Q
V
S
Q
Honey Bee
Apis mellifera
XP_001122147
624
70155
F492
V
K
L
S
D
F
G
F
C
A
Q
V
S
Q
E
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
S440
F
G
F
C
A
Q
L
S
P
E
Q
R
K
R
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T756
M
E
G
D
I
K
L
T
D
F
G
F
C
A
Q
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
T810
M
E
G
N
I
K
L
T
D
F
G
F
C
A
T
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
0
100
93.3
93.3
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
20
100
93.3
100
N.A.
13.3
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
0
0
0
7
7
0
0
60
0
% A
% Cys:
0
7
0
7
7
0
0
0
7
7
0
0
60
0
0
% C
% Asp:
7
47
0
14
7
7
0
14
60
0
0
0
0
0
7
% D
% Glu:
0
14
0
0
0
0
0
0
0
7
7
0
0
0
7
% E
% Phe:
14
7
7
7
0
7
7
7
7
60
0
60
0
0
0
% F
% Gly:
0
7
67
0
0
0
7
7
0
0
60
0
0
0
0
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
34
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
0
7
7
0
0
67
7
0
0
0
7
0
14
7
0
% K
% Leu:
40
0
7
7
0
0
67
0
0
0
7
7
0
7
7
% L
% Met:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
14
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
7
7
0
0
0
14
14
0
7
60
% Q
% Arg:
7
0
7
47
0
0
0
0
0
0
0
14
0
7
7
% R
% Ser:
0
0
0
7
7
7
7
54
7
0
0
0
14
14
0
% S
% Thr:
0
0
0
0
0
0
0
14
7
0
0
0
7
0
14
% T
% Val:
7
7
0
0
40
0
0
0
7
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _